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CCL3 (MIP-1 alpha) Monoclonal Antibody (DNT3CC), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-7532-82

2400.12 SEK valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Additional Details : Weight : 0.09500kg

Product Code. 15569366

  • 3600.00 SEK / 100µg
Estimated Shipment: 08-05-2024
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Description

Description

Description: This DNT3CC monoclonal antibody reacts with mouse CCL3. CCL3, also known as MIP-1 alpha (Macrophage Inflammatory Protein 1 alpha), is a member of the CC- subfamily of chemokines and is most closely related to CCL4, or MIP-1 beta. These proteins play critical roles in the recruitment of leukocytes to the site of inflammation. While both CCL3 and CCL4 will attract monocytes, macrophages, and dendritic cells, CCL3 preferentially attracts CD8+ T cells, while CD4+ T cells are more responsive to CCL4. In addition to its chemotactic functions, CCL3 induces inflammatory cytokine secretion, mast cell degranulation, and NK cell activation. It has also been reported to inhibit hematopoetic stem cell proliferation and may be responsible for the maintece of these cells in a quiescent state. CCL3 signaling is mediated by the G protein-coupled receptors CCR1, CCR4, and CCR5, which are shared with CCL4 and CCL5 (RANTES). Applications Reported: This DNT3CC antibody has been reported for use in intracellular staining followed by flow cytometric analysis. Applications Tested: This DNT3CC antibody has been tested intracellular staining of stimulated mouse spleen cells followed by flow cytometric analysis using the Intracellular Fixation & Permeabilization Buffer Set (cat. 88-8824) and protocol. Please refer to Best Protocols: Protocol A: Two step protocol for (cytoplasmic) intracellular proteins. This can be used at less than or equal to 0.5 μg per test.

CCL3 (MIP-1 alpha) Monoclonal antibody specifically detects CCL3 (MIP-1 alpha) in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

CCL3 (MIP-1 alpha)
Monoclonal
0.2 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P10855
Ccl3
Affinity chromatography
RUO
20302
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
DNT3CC
PerCP-eFluor 710
Ccl3
AI323804; C-C motif chemokine 3; C-C motif chemokine ligand 3; CCL3; chemokine (C-C motif) ligand 3; G0/G1 switch regulatory protein 19-1; G0S19-1; Heparin-binding chemotaxis protein; H-MIP-1-alpha; L2G25B; LD78ALPHA; LD78-alpha; LD78-alpha(4-69); Macrophage inflammatory protein 1 alpha (Small inducible cytokine A3); macrophage inflammatory protein 1-alpha; macrophage inflammatory protein-1alpha; MIP1 (a); mip1 alpha; MIP-1 alpha; MIP1-(a); MIP1A; MIP-1a; MIP-1alpha; MIP-1-alpha; MIP1-alpha; MIP-1-alpha(4-69); PAT 464.1; RP23-320E6.7; Scya3; SIS-alpha; SIS-beta; small inducible cytokine A3; small inducible cytokine A3 (homologous to mouse Mip-1a); small-inducible cytokine A3; Tonsillar lymphocyte LD78 alpha protein; TY-5
Rat
100 μg
Primary
Mouse
Antibody
IgG2a κ
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