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CD119 (IFN gamma Receptor 1) Monoclonal Antibody (GR-20), Functional Grade, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
31750.00 SEK - 158800.00 SEK
Specifications
Antigen | CD119 (IFN gamma Receptor 1) |
---|---|
Clone | GR-20 |
Concentration | 1 mg/mL |
Applications | Flow Cytometry, Functional Assay, Neutralization |
Classification | Monoclonal |
Description
The monoclonal antibody GR-20 recognizes mouse CD119 also known as IFN gamma receptor 1. CD119 heterodimerizes with IFN gamma receptor 2 (AF-1) forming the Class II cytokine receptor. The ligand IFN gamma binds IFN gamma receptor 1 subunit but signal transduction transpires via the IFN gamma receptor 2 subunit. The receptor is involved in host defense and expression is broad including B cells, NK cells, macrophages and dendritic cells as well as other non-hematopoietic cell types. The GR-20 antibody has been reported to block IFN gamma binding to CD119. Applications Reported: This GR-20 antibody has been reported for use in flow cytometric analysis and functional assays (blocking cytokine binding to the receptor). Storage and handling: Use in a sterile environment. Filtration: 0.2 ÎĽm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/ ÎĽg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC.
CD119 (IFN gamma Receptor 1) Monoclonal antibody specifically detects CD119 (IFN gamma Receptor 1) in Mouse samples. It is validated for Flow Cytometry, Functional Assay, NeutralizationSpecifications
CD119 (IFN gamma Receptor 1) | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with no preservative; pH 7.2 | |
antiviral protein, type 2; AVP, type 2; CD119; CD119 antigen; CDw119; Ifgr; IFN-gamma receptor 1; IFN-gammaR; IFN-gamma-R1; IFN-gamma-R-alpha; Ifngr; Ifngr1; IMD27A; IMD27B; immune interferon receptor 1; INF-g receptor; interferon gamma receptor 1; Interferon gamma receptor alpha-chain; interferon-gamma receptor 1; interferon-gamma receptor alpha chain; Nktar | |
IgG2a Îş | |
Affinity chromatography | |
Antibody |
GR-20 | |
Flow Cytometry, Functional Assay, Neutralization | |
Functional Grade | |
Rat | |
Mouse | |
P15261 | |
15979 | |
Primary | |
4° C | |
IFNGR1 |
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