CD134 (OX40) Rat anti-Mouse, Clone: OX-86, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 14-1341-85
Additional Details : Weight : 0.01000kg
DescriptionIt is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
|PBS with 0.09% sodium azide; pH 7.2|
|cluster designation 134, TNFRSF4|
|Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Neutralization, Western Blot|
For Research Use Only.