missing translation for 'onlineSavingsMsg'
Learn More

Invitrogen™ CD154 (CD40 Ligand) Monoclonal Antibody (MR1), PE, eBioscience™, Invitrogen™

Armenian Hamster Monoclonal Antibody

1200.00 SEK - 3320.00 SEK

Specifications

Antigen CD154 (CD40 Ligand)
Clone MR1
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
View More Specs

Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15208699
View Documents
Invitrogen™
12-1541-81
50 ÎĽg
1200.00 SEK
50µg
Please to purchase this item. Need a web account? Register with us today!
15218699
View Documents
Invitrogen™
12-1541-82
100 ÎĽg
2375.00 SEK
100µg
Please to purchase this item. Need a web account? Register with us today!
15228699
View Documents
Invitrogen™
12-1541-83
200 ÎĽg
3320.00 SEK
200µg
Please to purchase this item. Need a web account? Register with us today!
Description

Description

Description: The MR1 monoclonal antibody reacts with mouse CD154, a 39 kDa transmembrane glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction. CD154-interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle. For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1. Applications Reported: The MR1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This MR1 antibody has been tested by flow cytometric analysis of stimulated splenocytes. This can be used at less than or equal to 0.25 ÎĽg per test. A test is defined as the amount (ÎĽg) of antibody that will stain a cell sample in a final volume of 100 ÎĽL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 ÎĽm post-manufacturing filtered.

CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen expressed on the surface of T cells. The CD40 Ligand stimulates B cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 Ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2.
Specifications
Show More
Videos
SDS
Documents

Documents

Product Certifications

For Research Use Only.

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title
Invitrogen™ CD154 (CD40 Ligand) Monoclonal Antibody (MR1), PE, eBioscience™, Invitrogen™

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.