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CD16/CD32 Rat anti-Mouse, Biotin, Clone: 93, eBioscience™

Rat Monoclonal Antibody

708.00 SEK - 4145.00 SEK

Specifications

Antigen CD16/CD32
Clone 93
Target Species Mouse
Conjugate Biotin
Isotype IgG2a, lambda
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Products 4
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15229469
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Affymetrix eBioscience
13-0161-81
50 μg
708.00 SEK
50µg
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Estimated Shipment: 09-09-2021
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15239469
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Affymetrix eBioscience
13-0161-82
100 μg
1314.00 SEK
100µg
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Estimated Shipment: 09-09-2021
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15249469
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Affymetrix eBioscience
13-0161-85
500 μg
2320.00 SEK
500µg
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Estimated Shipment: 09-09-2021
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15259469
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Affymetrix eBioscience
13-0161-86
1 mg
4145.00 SEK
1mg
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Estimated Shipment: 09-09-2021
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Description

Description

Description: The 93 monoclonal antibody reacts with an epitope shared by mouse CD16 and CD32. CD16 (Fc gamma III Receptor) and CD32 (Fc gamma II Receptor) are the low affinity receptors for the mouse IgG Fc portion and are expressed by B cells, monocyte/macrophages, NK cells, and neutrophils. Applications Reported: The 93 antibody has been reported for use in flow cytometric analysis. Applications Tested: The 93 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.125 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered.

CD16 is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by natural killer (NK) cells, and some T cells and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC (antibody dependent cell mediated cytotoxicity) by NK cells. IN comparison, CD32 is a 40 kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII), and mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets. Further, CD32 is involved in the phagocytosis of immune complexes, the regulation of antibody production by B-cells, and variations of the CD32 gene may increase vulnerability to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms of CD32 have been found.
Specifications

Specifications

CD16/CD32
Mouse
IgG2a, lambda
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
93
Biotin
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO
SDS
Product Certifications

For Research Use Only.