missing translation for 'onlineSavingsMsg'
Learn More
Learn More
CD161 Mouse anti-Human, APC, Clone: HP-3G10, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 17-1619-42
Additional Details : Weight : 0.23750kg
Description
Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells. {ECO:0000269; PubMed:16455998, ECO:0000269; PubMed:16925668, ECO:0000269; PubMed:8077657}.Specifications
| CD161 | |
| Monoclonal | |
| 5 μL/Test | |
| PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
| Q12918 | |
| Ly55a, NKR-P1A, NKRP12, Nkrp1-a, Nkrp1a | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| Antibody | |
| Monoclonal | |
| Human |
| Flow Cytometry | |
| HP-3G10 | |
| APC | |
| KLRB1 | |
| Liquid | |
| KLRB1 | |
| IgG1, kappa | |
| 100 Tests | |
| 4° C, store in dark, DO NOT FREEZE! | |
| Primary | |
| 3820 |
For Research Use Only.