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CD235ab (Glycophorin A/B) Mouse, anti-Human, PE, Clone: HIR2 (GA-R2), STEMCELL Technologies

Mouse Monoclonal Antibody

Encompass_Preferred

POA - 4893.75 SEK

Specifications

Antigen CD235ab (Glycophorin A/B)
Clone HIR2 (GA-R2)
Applications Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Conjugate PE
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17109111
Encompass_Preferred
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Stemcell Technologies
60111PE.1
25 ÎĽg
POA
25µg
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17199101
Encompass_Preferred
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Stemcell Technologies
60111PE
100 ÎĽg
4893.75 SEK
100µg
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Description

Description

  • The HIR2 (GA-R2) antibody recognizes an epitope common to the N-terminal region of human CD235a (glycophorin A) and CD235b (glycophorin B), homologous type I sialoglycoproteins of the erythrocyte (red blood cell) membrane that bear the antigenic determinants for the MN and Ss blood groups
  • CD235ab is expressed on early- and late-stage erythroblasts, mature erythrocytes, and erythroid cell lines such as K562 and HEL, but not on other cell types
  • CD235a is abundantly expressed whereas CD235b is a relatively minor membrane component
  • The proteins are believed to provide a large mucin-like surface to erythrocytes that acts to minimize aggregation in the circulation
  • The HIR2 antibody binds with higher affinity to CD235a than CD235b, and agglutinates untreated erythrocytes
Specifications

Specifications

CD235ab (Glycophorin A/B)
Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
PE
Human
Primary
HIR2 (GA-R2)
Monoclonal
Mouse
IgG2b Îş
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