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CD299 (DC-SIGN/L) Monoclonal Antibody (16E7), APC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand: Invitrogen 17-2999-42

Product Code. 15528076

3570.00 SEK / 100 tests

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Description

Description: The 16E7 monoclonal antibody recognizes human CD299, which is also known as DC-SIGNR or L-SIGN. A homolog of DC-SIGN, CD299 is an oligomeric type II transmembrane protein expressed on dendritic cells, macrophages in the lung, and endothelial cells in the liver. This C-type lectin binds ICAM-3 to mediate the interaction between dendritic cells and T cells. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection. Applications Reported: This 16E7 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 16E7 antibody has been pre-titrated and tested by flow cytometric analysis of normal human monocyte-derived dendritic cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.

CD299 (DC-SIGN/L) Monoclonal antibody specifically detects CD299 (DC-SIGN/L) in Human samples. It is validated for Flow Cytometry.

Specifications

Antigen	CD299 (DC-SIGN/L)
Classification	Monoclonal
Concentration	5 μL/Test
Formulation	PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.	Q9H2X3
Gene Symbols	CLEC4M
Purification Method	Affinity chromatography
Regulatory Status	RUO
Gene ID (Entrez)	10332
Content And Storage	4° C, store in dark, DO NOT FREEZE!
Form	Liquid

Applications	Flow Cytometry
Clone	16E7
Conjugate	APC
Gene	CLEC4M
Gene Alias	CD209 antigen-like protein 1; Cd209b; CD209b antigen; CD209L; CD209L1; CD299; CD299 antigen; CLEC4M; C-type lectin domain family 4 member M; C-type lectin domain family 4, member M; DC-SIGN2; DCSIGNR; DC-SIGNR; DC-SIGN-related protein; Dendritic cell-specific ICAM-3-grabbing non-integrin 2; HP10347; liver/lymph node-specific ICAM-3 grabbing non-integrin; liver/lymph node-specific ICAM-3-grabbing non-integrin; LSIGN; L-SIGN; mannose binding C-type lectin DC-SIGNR; MGC129964; MGC47866
Host Species	Mouse
Quantity	100 Tests
Primary or Secondary	Primary
Target Species	Human
Product Type	Antibody
Isotype	IgG2a κ

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CD299 (DC-SIGN/L) Monoclonal Antibody (16E7), APC, eBioscience™, Invitrogen™

Description

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