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CD3 Mouse, anti-Human, PE, Clone: UCHT1, STEMCELL Technologies
Mouse Monoclonal Antibody

1486.35 SEK - 13853.70 SEK
Specifications
Antigen | CD3 |
---|---|
Clone | UCHT1 |
Applications | Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence |
Classification | Monoclonal |
Conjugate | PE |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17148421
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Stemcell Technologies
60011PE.1 |
25 Tests |
1486.35 SEK
25 tests |
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17138421
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Stemcell Technologies
60011PE |
100 Tests |
4873.50 SEK
100 tests |
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17177611
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Stemcell Technologies
100-0449 |
500 Tests |
13853.70 SEK
500 tests |
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Description
- The UCHT1 antibody reacts with the ∼20 kDa CD3ε subunit of the human T cell receptor (TCR)/CD3 complex, which is expressed on the surface of ∼95% of mature T cells and NKT cells, and variably onthymocytes
- A majority of T cell neoplasms also express CD3
- The CD3 complex, which is assembled from combinations of CD3γ, δ, ε, η, and ζ subunits, associates non-covalently with the TCR and is involved in transducing antigen recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR
- Activation of T cells by the TCR involves the cytoplasmic tails of the CD3 subunits, which are structurally related type 1 transmembrane proteins and members of the immunoglobulin superfamily
- Mutations in the CD3 subunits have been associated with various immunodeficiency disorders including severe combined immunodeficiency (SCID)
Specifications
CD3 | |
Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence | |
PE | |
Chimpanzee, Human |
UCHT1 | |
Monoclonal | |
Mouse | |
Primary |
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Product Title
CD3 Mouse, anti-Human, PE, Clone: UCHT1, STEMCELL Technologies