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CD3 Mouse, anti-Human, PE, Clone: UCHT1, STEMCELL Technologies

Mouse Monoclonal Antibody

Encompass_Preferred

1486.35 SEK - 13853.70 SEK

Specifications

Antigen CD3
Clone UCHT1
Applications Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Conjugate PE
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17148421
Encompass_Preferred
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Stemcell Technologies
60011PE.1
25 Tests
1486.35 SEK
25 tests
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17138421
Encompass_Preferred
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Stemcell Technologies
60011PE
100 Tests
4873.50 SEK
100 tests
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17177611
Encompass_Preferred
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Stemcell Technologies
100-0449
500 Tests
13853.70 SEK
500 tests
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Description

Description

  • The UCHT1 antibody reacts with the ∼20 kDa CD3ε subunit of the human T cell receptor (TCR)/CD3 complex, which is expressed on the surface of ∼95% of mature T cells and NKT cells, and variably onthymocytes
  • A majority of T cell neoplasms also express CD3
  • The CD3 complex, which is assembled from combinations of CD3γ, δ, ε, η, and ζ subunits, associates non-covalently with the TCR and is involved in transducing antigen recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR
  • Activation of T cells by the TCR involves the cytoplasmic tails of the CD3 subunits, which are structurally related type 1 transmembrane proteins and members of the immunoglobulin superfamily
  • Mutations in the CD3 subunits have been associated with various immunodeficiency disorders including severe combined immunodeficiency (SCID)
Specifications

Specifications

CD3
Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
PE
Chimpanzee, Human
UCHT1
Monoclonal
Mouse
Primary
Videos
SDS
Documents

Documents

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