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CD46 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 12494-1-AP-20UL
Additional Details : Weight : 0.00010kg
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DescriptionCD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.
|CD46, MCP, Membrane cofactor protein, MIC10, TLX, TRA2.10|
|Antigen Affinity Chromatography|
|Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)|
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|CD46 Fusion Protein Ag3131|