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CD7 Mouse anti-Human, Mouse, Clone: 2A4E6, Proteintech

Mouse Monoclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen CD7
Clone 2A4E6
Concentration 1.5 mg/mL
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16887215
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Proteintech
60209-2-IG-20UL
20 μL
1656.73 SEK
20µL
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Estimated Shipment: 02-04-2024
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16877215
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Proteintech
60209-2-IG-150UL
150 μL
4721.67 SEK
150µL
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Estimated Shipment: 02-04-2024
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Description

Description

CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily. CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on maligt B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3′-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Expression of CD7 is an important marker used in leukemia diagnostics.
Specifications

Specifications

CD7
1.5 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
CD7, CD7 molecule, GP40, LEU 9, T cell antigen CD7, T cell leukemia antigen, T cell surface antigen Leu 9, Tp40, TP41
CD7
IgG1
Protein A
Antibody
2A4E6
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Mouse
Mouse, Human
P09564, P50283
12516, 924
CD7 Fusion Protein Ag1805
Primary
-20°C
CD7
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