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  6. CD71 (Transferrin Receptor) Mouse, anti-Human, APC, Clone: OKT9, STEMCELL Technologies

CD71 (Transferrin Receptor) Mouse, anti-Human, APC, Clone: OKT9, STEMCELL Technologies

Mouse Monoclonal Antibody

Encompass_Preferred

2182.95 SEK - 4594.05 SEK

Specifications

Antigen CD71 (Transferrin Receptor)
Clone OKT9
Applications Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Conjugate APC
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
17109051
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Stemcell Technologies
60106AZ.1 		25 Tests
2182.95 SEK
25 tests
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17199041
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Stemcell Technologies
60106AZ 		100 Tests
4594.05 SEK
100 tests
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Description

Description

  • The OKT9 antibody reacts with CD71 (transferrin receptor), an ∼180 - 190 kDa disulfide-bonded homodimer and type 2 transmembrane glycoprotein expressed at high levels on a broad range of actively proliferating cells, as well as reticulocytes, monocytes, macrophages and marrow stromal cells
  • Surface levels are low on resting leukocytes but are upregulated on lymphocytes, monocytes and macrophages following antigen or mitogen stimulation
  • Expression is lost during differentiation of reticulocytes into mature erythrocytes
  • CD71 mediates uptake of transferrin–iron complexes through receptor-mediated endocytosis and recycling of the apotransferrin–receptor complex to the cell surface
  • It has also served as a target for drug delivery
  • The OKT9 antibody binds an epitope that reportedly overlaps with that of antibody clone CY1G4 but is distinct from the ligand binding site for transferrin
Specifications

Specifications

CD71 (Transferrin Receptor)
Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
APC
Human
Primary
OKT9
Monoclonal
Mouse
IgG1 κ
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Documents

Documents

Product Certifications
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