missing translation for 'onlineSavingsMsg'
Learn More
Learn More
CD71 (Transferrin Receptor) Mouse, anti-Human, APC, Clone: OKT9, STEMCELL Technologies
Mouse Monoclonal Antibody
2108.70 SEK - 4438.80 SEK
Specifications
Antigen | CD71 (Transferrin Receptor) |
---|---|
Clone | OKT9 |
Applications | Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence |
Classification | Monoclonal |
Conjugate | APC |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17109051
|
Stemcell Technologies
60106AZ.1 |
25 Tests |
2108.70 SEK
25 tests |
Estimated Shipment: 17-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
17199041
|
Stemcell Technologies
60106AZ |
100 Tests |
4438.80 SEK
100 tests |
Estimated Shipment: 17-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
- The OKT9 antibody reacts with CD71 (transferrin receptor), an ∼180 - 190 kDa disulfide-bonded homodimer and type 2 transmembrane glycoprotein expressed at high levels on a broad range of actively proliferating cells, as well as reticulocytes, monocytes, macrophages and marrow stromal cells
- Surface levels are low on resting leukocytes but are upregulated on lymphocytes, monocytes and macrophages following antigen or mitogen stimulation
- Expression is lost during differentiation of reticulocytes into mature erythrocytes
- CD71 mediates uptake of transferrin–iron complexes through receptor-mediated endocytosis and recycling of the apotransferrin–receptor complex to the cell surface
- It has also served as a target for drug delivery
- The OKT9 antibody binds an epitope that reportedly overlaps with that of antibody clone CY1G4 but is distinct from the ligand binding site for transferrin
Specifications
CD71 (Transferrin Receptor) | |
Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence | |
APC | |
Human | |
Primary |
OKT9 | |
Monoclonal | |
Mouse | |
IgG1 κ |