missing translation for 'onlineSavingsMsg'
Learn More

Claudin 18 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 21126-1-AP-150UL

Additional Details : Weight : 0.00010kg

 View more versions of this product

Product Code. 16880725

  • 3313.85 SEK / 150µL
Estimated Shipment: 02-12-2021

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Claudin-18 is a tight junction protein expressed as lung-and stomach-specific isoforms which are generated by alternative splicing of the claudin-18 gene. The lung-specific form is a downstream target gene regulated by the T/EBP/NKX2.1 transcription factor. A splice variant lacking the C-terminal cytoplasmic domain also exists in mouse, but has not been confirmed in human. Human claudin-18 demonstrates 88% amino acid sequence identity to the mouse protein. Immunohistochemical studies have demonstrated complete membrane localization of claudin-18 in lung and stomach epithelial cells, while electron microscopy has shown that it is concentrated in the cell-cell borders of these cells. These features suggest a potentially important role for claudin-18 in the structure and function of tight junctions in the lung and stomach. Claudin-18 expression has also been reported in the inner ear.
Specifications

Specifications

Claudin 18
0.25 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P56856, P56857
claudin 18, CLDN18, SFTA5, SFTPJ
Rabbit
IgG
150 μL
-20°C
Primary
315953, 51208, 56492
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
CLDN18
Liquid
Cldn18
Claudin 18 Fusion Protein Ag15517
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Videos
SDS
Documents
Certificates
Special Offers

Special Offers