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CRTC1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 27647-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16885755

  • 1355.00 SEK / 20µL
Estimated Shipment: 03-04-2023
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Description

Description

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites.Acts as a coactivator, in the SIK/TORC signaling pathway,being active when dephosphorylated and acts independently of CREB1 ′Ser-133′ phosphorylation.Enhances the interaction of CREB1 with TAF4.Regulates the expression of specific CREB-activated genes such as the steroidogenic gene,StAR.Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells.Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintece at the Schaffer collateral-CA1 synapses.May be required for dendritic growth of developing cortical neurons.
Specifications

Specifications

CRTC1
Polyclonal
Unconjugated
CRTC1
CRTC1, KIAA0616, MECT1, TORC 1, TORC1, Transducer of CREB protein 1, WAMTP1
Rabbit
Antigen Affinity Chromatography
RUO
23373, 382056
-20°C
Liquid
Western Blot
0.4 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q68ED7, Q6UUV9
Crtc1
CRTC1 Fusion Protein Ag26494
20 μL
Primary
Mouse, Human
Antibody
IgG
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