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Cyclosporin A, 99+%, Thermo Scientific™
Cyclosporin A, CAS # 59865-13-3, is a compound that shows immunosuppressive, antifungal, antirheumatic, and dermatologic activities. It is also a calcineurin and enzyme inhibitor.
2387.65 SEK - 5345.65 SEK
Kemiska identifierare
| CAS | 59865-13-3 |
|---|---|
| Molekylformel | C62H111N11O12 |
| Molekylvikt (g/mol) | 1202.64 |
| MDL-nummer | MFCD00274558 |
| InChI-nyckel | PMATZTZNYRCHOR-IMVLJIQENA-N |
| Synonym | Cyclosporine A; Antibiotic S 7481F1 |
| PubChem CID | 132274082 |
| IUPAC-namn | 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone |
| LEDER | CCC1NC(=O)C(C(O)C(C)C\C=C\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C |
| Produktkod | Brand | Kvantitet | Pris | Kvantitet och tillgänglighet | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktkod | Brand | Kvantitet | Pris | Kvantitet och tillgänglighet | |||||
|
15475449
|
Thermo Scientific Alfa Aesar
J63191.03 |
1g |
 2659.57 SEK 2387.65 SEK / 1g Save 271.92 SEK 10% Av |
Vänligen Logga in för att beställa denna produkten. Behöver du ett Webbkonto? Registrera ditt konto idag! | |||||
|
15485449
|
Thermo Scientific Alfa Aesar
J63191.06 |
5g |
5953.44 SEK 5345.65 SEK / 5g Save 607.79 SEK 10% Av |
Vänligen Logga in för att beställa denna produkten. Behöver du ett Webbkonto? Registrera ditt konto idag! | |||||
Beskrivning
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
• Cyclosporin A is a non-polar cyclic oligopeptide produced by the fungus Tolypocladium inflatum
Applications
• Cyclosporin A demonstrates immunosuppressive, antifungal, antirheumatic, and dermatologic activities
• In in vivo and in vitro studies it displays tumorigenicity
• This compound has also been shown to display anti-asthmatic and anticoronaviral activities
• It inhibits phosphoprotein phosphatase
• Cyclosporin A binds to the cellular protein cytophilin and inhibits the enzyme calcineurin
• Furthermore, it can induce apoptosis and inhibit angiogenesis induced by VEGF
• It exerts potent immunosuppressive activity on T immune cells, and causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle
• It also suppresses the hepatitis C virus replication in cultured hepatocytes
Kemiska identifierare
| 59865-13-3 | |
| 1202.64 | |
| PMATZTZNYRCHOR-IMVLJIQENA-N | |
| 132274082 | |
| CCC1NC(=O)C(C(O)C(C)C\C=C\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C |
| C62H111N11O12 | |
| MFCD00274558 | |
| Cyclosporine A; Antibiotic S 7481F1 | |
| 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone |
Specifikationer
| Cyclosporin A | |
| White | |
| MFCD00274558 | |
| 14,2752 | |
| Soluble in dimethyl sulfoxide and ethanol; Insoluble in water. | |
| CCC1NC(=O)C(C(O)C(C)C\C=C\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C | |
| 1202.64 | |
| 1202.61 |
| 59865-13-3 | |
| C62H111N11O12 | |
| 3647785 | |
| Cyclosporine A; Antibiotic S 7481F1 | |
| PMATZTZNYRCHOR-IMVLJIQENA-N | |
| 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone | |
| 132274082 | |
| ≥99% |
Säkerhet och hantering
GHS H Statement
H361-H302
Suspected of damaging fertility or the unborn child.
Harmful if swallowed.
P201-P202-P264b-P270-P281-P301+P312-P308+P313-P330-P501c
H302-H350-H360FD
missing translation for 'einecsNumber' : 611-907-1
missing translation for 'rtecsNumber' : GZ4120000
missing translation for 'tsca' : No
Rekommenderad förvaring : Store at -20°C
RUO – Research Use Only
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Produkttitel
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