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Cyclosporin A, 99+%, Thermo Scientific™

Cyclosporin A, CAS # 59865-13-3, is a compound that shows immunosuppressive, antifungal, antirheumatic, and dermatologic activities. It is also a calcineurin and enzyme inhibitor.

2785.00 SEK - 6240.00 SEK

Kemiska identifierare

CAS 59865-13-3
Molekylformel C62H111N11O12
Molekylvikt (g/mol) 1202.64
MDL-nummer MFCD00274558
InChI-nyckel PMATZTZNYRCHOR-IMVLJIQENA-N
Synonym Cyclosporine A; Antibiotic S 7481F1
PubChem CID 132274082
IUPAC-namn 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone
LEDER CCC1NC(=O)C(C(O)C(C)C\C=C\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C
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Thermo Scientific Alfa Aesar
J63191.03 		1g
2785.00 SEK
1g
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Thermo Scientific Alfa Aesar
J63191.06 		5g
6240.00 SEK
5g
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Beskrivning

Beskrivning

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description
• Cyclosporin A is a non-polar cyclic oligopeptide produced by the fungus Tolypocladium inflatum
Applications
• Cyclosporin A demonstrates immunosuppressive, antifungal, antirheumatic, and dermatologic activities
• In in vivo and in vitro studies it displays tumorigenicity
• This compound has also been shown to display anti-asthmatic and anticoronaviral activities
• It inhibits phosphoprotein phosphatase
• Cyclosporin A binds to the cellular protein cytophilin and inhibits the enzyme calcineurin
• Furthermore, it can induce apoptosis and inhibit angiogenesis induced by VEGF
• It exerts potent immunosuppressive activity on T immune cells, and causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle
• It also suppresses the hepatitis C virus replication in cultured hepatocytes
Specifikationer

Kemiska identifierare

59865-13-3
1202.64
PMATZTZNYRCHOR-IMVLJIQENA-N
132274082
CCC1NC(=O)C(C(O)C(C)C\C=C\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C
C62H111N11O12
MFCD00274558
Cyclosporine A; Antibiotic S 7481F1
30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone

Specifikationer

Cyclosporin A
White
MFCD00274558
14,2752
Soluble in dimethyl sulfoxide and ethanol; Insoluble in water.
CCC1NC(=O)C(C(O)C(C)C\C=C\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C
1202.64
1202.61
59865-13-3
C62H111N11O12
3647785
Cyclosporine A; Antibiotic S 7481F1
PMATZTZNYRCHOR-IMVLJIQENA-N
30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone
132274082
≥99%
Filmer
Säkerhet och hantering

Säkerhet och hantering

GHS H Statement
H361-H302
Suspected of damaging fertility or the unborn child.
Harmful if swallowed.

P201-P202-P264b-P270-P281-P301+P312-P308+P313-P330-P501c

H302-H350-H360FD

missing translation for 'einecsNumber' : 611-907-1

missing translation for 'rtecsNumber' : GZ4120000

missing translation for 'tsca' : No

Rekommenderad förvaring : Store at -20°C

SDS
Dokument

Dokument

Produktspecifikationer

RUO – Research Use Only

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