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CYP11A1 Rabbit anti-Human, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 13363-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16881524

  • 1355.00 SEK / 20µL
Estimated Shipment: 28-03-2023
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Description

Description

CYP11A1, also known as cytochrome P450C11A1, cytochrome P450scc and cytochrome P450, subfamily XIA, is an enzyme that catalyzes the first step of steroid biosynthesis under the modulation of cAMP signal. CYP11A1 in steroidogenic cells converts cholesterol to pregnenolone, which is determined by hormonal control of cholesterol availability. Expression of the CYP11A1 gene is controlled by the transcription factor SF-1, and the upstream SF-1 binding site in the CYP11A1 gene is required for hormonal stimulation. c-Jun and SF-1 may act synergistically to activate CYP11A1 gene expression. Both Forskolin and 8-Br-cAMPS elevate CYP11A1 mRNA levels in the interstitial cell monolayer, which has a fully functional adenylate cyclase.
Specifications

Specifications

CYP11A1
Polyclonal
Unconjugated
CYP11A1
Cholesterol desmolase, CYP11A, CYP11A1, CYPXIA1, Cytochrome P450 11A1, Cytochrome P450(scc), P450SCC
Rabbit
Antigen Affinity Chromatography
RUO
1583, 29680
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.2 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P05108, P14137
CYP11A1
CYP11A1 Fusion Protein Ag4182
20 μL
Primary
Human, Rat
Antibody
IgG
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