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Eurofins DiscoverX DDR2 Protein, Active

Active, N-terminal His6-tagged, recombinant, human DDR2 amino acids 467-end, for use in Kinase Assays.

6046.30 SEK - 46147.75 SEK

Specifications

Formulation	mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol)	48 kDa
Species	Human
Recombinant	Recombinant
Protein Tag	N-terminal 6His

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Products 2

Product Code	Brand	Quantity	Price	Quantity & Availability
Product Code	Brand	Quantity	Price	Quantity & Availability
17360374 View Documents missing translation for 'viewProductCertificates'	Eurofins DiscoverX 14-579	10 μg	6046.30 SEK 10µg View alternative products Save Up to »		Please sign in to purchase this item. Need a web account? Register with us today!

17370374 View Documents missing translation for 'viewProductCertificates'	Eurofins DiscoverX 14-579M	250 μg	46147.75 SEK 250µg View alternative products Save Up to »		Please sign in to purchase this item. Need a web account? Register with us today!

Description

Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.

GenBank NM_006182. The recombinant protein contains the amino acid substitution S642A (native coordinates) with respect toGenBank NM_006182. This conflict is reported inGenBank accession n° NM_022563, BC052998, BQ678490, BU168475 and BQ682363.

Specifications

Formulation	mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Species	Human
Protein Tag	N-terminal 6His
Protein Form	Truncated
Protein	DDR2, active

Molecular Weight (g/mol)	48 kDa
Recombinant	Recombinant
Expression System	Recombinant enzyme expressed in Sf21 insect cells
Purity or Quality Grade	≥46%

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Eurofins DiscoverX DDR2 Protein, Active

Specifications

Description

Specifications

Documents