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DDX1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11357-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888373

  • 1236.20 SEK / 20µL
Estimated Shipment: 02-12-2021

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Description

Description

DDX1 (ATP-dependent RNA helicase DDX1) acts as an ATP-dependent RNA helicase. It is able to unwind both RNA-RNA and RNA-DNA duplexes. DDX1 possesses 5′ single-stranded RNA overhand nuclease activity and ATPase activity on various RNA, but not DNA polynucleotides. DDX1, together with RELA, acts as a coactivator to enhance NF-kappa-b-mediated transcriptional activation. It also acts as a positive transcriptional regulator of cyclin CCND2 expression. It binds to the cyclin CCND2 promoter region. DDX1 is a component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double stranded RNA and plays a role in activation of a cascade of antiviral responses including the induction of proinflammatory cytokines via the adapter molecule TICAM1.
Specifications

Specifications

DDX1
0.39 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q641Y8, Q91VR5, Q92499
DBP RB, DDX1, DEAD box protein 1, UKVH5d
Rabbit
IgG
20 μL
-20°C
Primary
104721, 1653, 84474
Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation
Unconjugated
DDX1
Liquid
DDX1
DDX1 Fusion Protein Ag1887
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Rat, Human
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