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Dexamethasone 21-phosphate disodium salt, 98%, Thermo Scientific™

Dexamethasone 21-phosphate disodium salt, CAS # 2392-39-4, is a synthetic adrenal glucocorticoid with potent anti-inflammatory activity.

1249.65 SEK - 4206.36 SEK

Kemiska identifierare

CAS 2392-39-4
Molekylformel C22H28FNa2O8P
Molekylvikt (g/mol) 516.41
MDL-nummer MFCD00079105
InChI-nyckel PLCQGRYPOISRTQ-FCJDYXGNSA-L
Synonym dexamethasone sodium phosphate, dexamethasone 21-phosphate disodium salt, dalalone, dexadreson, dexagro, megacort, soldesam, spersadox, decdan, solu-decadron
PubChem CID 16961
ChEBI CHEBI:4462
IUPAC-namn disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
LEDER CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]
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J64083.03
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J64083.06
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Beskrivning

Beskrivning

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description
Dexamethasone 21-phosphate disodium salt is a sodium phosphate salt form of dexamethasone, considered to be a synthetic adrenal glucocorticoid with anti-inflammatory activity
Application
Dexamethasone 21-phosphate disodium salt binds to specific nuclear steroid receptors, interfering with NF-kB activation and apoptotic pathways
It acts as an inducer of apoptosis and inhibitor of the sodium phosphate symporter
It has been used as a positive control to study its effects on ocular shedding of herpes simplex virus type 1 in the induced reactivation and spontaneous shedding rabbit models
This compound is used to study its protective effects against cisplatin-induced ototoxicity in the inner ear of guinea pigs
Specifikationer

Kemiska identifierare

2392-39-4
516.41
PLCQGRYPOISRTQ-FCJDYXGNSA-L
16961
disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
C22H28FNa2O8P
MFCD00079105
dexamethasone sodium phosphate, dexamethasone 21-phosphate disodium salt, dalalone, dexadreson, dexagro, megacort, soldesam, spersadox, decdan, solu-decadron
CHEBI:4462
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]

Specifikationer

Dexamethasone 21-phosphate disodium salt
C22H28FNa2O8P
6473066
dexamethasone sodium phosphate, dexamethasone 21-phosphate disodium salt, dalalone, dexadreson, dexagro, megacort, soldesam, spersadox, decdan, solu-decadron
PLCQGRYPOISRTQ-FCJDYXGNSA-L
disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
16961
516.4
2392-39-4
MFCD00079105
142943
Soluble in water. Slightly soluble in ethanol. Insoluble in dichloromethane.
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]
516.41
CHEBI:4462
98%
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Säkerhet och hantering

Säkerhet och hantering

Harmful if swallowed, Suspected of damaging the unborn child, May cause damage to organs through prolonged or repeated exposure

Acute toxicity (category 4), Reproductive toxicity (category 2), Specific target organ toxicity after repeated exposure (category 2)

missing translation for 'einecsNumber' : 219-243-0

missing translation for 'rtecsNumber' : TU4056000

missing translation for 'tsca' : Yes

Rekommenderad förvaring : Keep cold

SDS
Dokument

Dokument

Produktspecifikationer

RUO – Research Use Only

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