missing translation for 'onlineSavingsMsg'
Learn More

DLGAP3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 55056-1-AP-150UL

Additional Details : Weight : 0.00010kg

 View more versions of this product

Product Code. 16886495

  • 3313.85 SEK / 150µL
Estimated Shipment: 08-12-2021

Please to purchase this item. Need a web account? Register with us today!


Description

Description

The antibody has no cross reaction to other DLGAP members.

SAP90/PSD-95-associated protein 3 (SAPAP3, also known as DLGAP3) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP3 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). Both SAPAP3 protein and mRNA are targeted to dendrites, whereas SAPAP1, -2, and -4 mRNAs are detected mainly in cell bodies. Recent experiments have suggested that SAPAP3 may be involved in obsessive-compulsive disorder (OCD), as mice lacking SAPAP3 exhibited OCD-like symptoms which could be relieved by lentiviral-mediated selective expression of SAPAP3 in the striatum of SAPAP3-mutant mice. At least two isoforms are known to exist.
Specifications

Specifications

DLGAP3
0.17 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O95886, Q6PFD5
DAP 3, DAP3, DLGAP3, PSD 95/SAP90 binding protein 3, SAPAP3
Rabbit
IgG
150 μL
-20°C
Primary
242667, 58512
Western Blot
Unconjugated
DLGAP3
Liquid
DLGAP3
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Videos
SDS
Documents
Certificates
Special Offers

Special Offers