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DLL4 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 21584-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16881185

  • 3313.85 SEK / 150µL
Estimated Shipment: 06-12-2021

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Description

Description

DLL4 (Delta-like ligand 4, Delta-4) is a homologue of the Drosophila delta protein, and functions as a transmembrane bound ligand to the notch receptor Notch1. DLL4 is expressed in the vasculature and plays a critical role in vascular development. It is induced by vascular endothelial growth factor (VEGF), as a negative feedback regulator to regulate angiogenic sprouting and promote the formulation of a differentiated vascular network. DLL4 has been found to be strongly expressed in tumor vessels of clear-cell renal tumors and bladder cancer, and inhibition of DLL4 results in increased vascular proliferation but defective maturation. This in turn leads to a decrease in tumor growth, with no apparent toxicity.
Specifications

Specifications

DLL4
0.22 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9JI71, Q9NR61
delta like 4 (Drosophila), Delta like protein 4, Delta4, DLL4, Drosophila Delta homolog 4, hdelta2
Rabbit
IgG
150 μL
-20°C
Primary
54485, 54567
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
DLL4
Liquid
Dll4
DLL4 Fusion Protein Ag16140
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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