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Doxycycline Hydrochloride, MP Biomedicals™
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Quantity:
10 g
Description
Doxycycline Hydrochloride is a synthetic oxytetracycline derivative and is a member of the tetracycline antibiotics group. It shows antiprotozoal properties and is a potent inhibitor of MMPs (matrix metallo-proteinases), such as type 1 collagenase. It is used to treat a variety of infections and for other biomedical applications.
- Treats chronic prostatitis, sinusitis, pelvic inflammatory disease, acne, rosacea, and rickettsial infections
- Inhibits the inflammatory response of Lyme disease
- Used in prophylaxis of anthrax (caused by Bacillus anthracis)
- Effective against Yersinia pestis
- Inhibits collagen synthesis
- Used in studies on wound healing and tissue remodeling
- Eliminates Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs
- Eliminates Ixodes scapularis ticks
Specifications
Physical Form | Powder |
CAS | 10592-13-9 |
Molecular Formula | C22H25ClN2O8 |
MDL Number | MFCD03427564 |
Synonym | Biocamycin, Doxigalumicina, Doxycycline hyclate, Doxy-II, Midoxin, Novadox, Retens, Tetradox, Vibradox, Hydramycin, 2-Naphthacenecarboxamide, 4-(dimethylamino)- 1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride |
Solubility Information | Soluble in water (10mg/mL, clear, yellowish to yellowish-green solution) and DMSO (50mg/mL). |
InChI Key | VLUQVUWDECWBTL-UQVCFKGQSA-N |
SMILES | [Cl-].C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H]([NH+](C)C)C(=O)\C(=C(/N)O)C(=O)[C@@]3(O)C(=O)C2=C(O)C2=C(O)C=CC=C12 |
IUPAC Name | [(1S,4aR,11R,11aR,12S,12aR)-3-carbamoyl-4,4a,6,7,12-pentahydroxy-11-methyl-2,5-dioxo-11,11a,12,12a-tetrahydro-1H-tetracen-1-yl]-dimethylazanium;chloride |
Molecular Weight (g/mol) | 480.90 |
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Safety and Handling
Product Identifier
- Doxycycline Hydrochloride
- Warning
- Acute toxicity Category 4
- Skin corrosion/irritation Category 2
- Serious eye damage/eye irritation Category 2
- Specific target organ toxicity Category 3
- H302 + H312-Harmful if swallowed or in contact with skin.
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P321-Specific treatment (see on this label).
- P405-Store locked up.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
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