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Doxycycline Hydrochloride, MP Biomedicals™

Catalog Number 11420455
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10 g
This item is not returnable. View return policy
This item is not returnable. View return policy

More active biologically than the corresponding 6b-epimer hydrochloride. Doxycycline Hydrochloride, MP Biomedicals is a broad spectrum antibiotic effective against gram-positive and gram-negative bacteria. It is a derivative of oxytetracycline used to inh

Doxycycline Hydrochloride is a synthetic oxytetracycline derivative and is a member of the tetracycline antibiotics group. It shows antiprotozoal properties and is a potent inhibitor of MMPs (matrix metallo-proteinases), such as type 1 collagenase. It is used to treat a variety of infections and for other biomedical applications.

  • Treats chronic prostatitis, sinusitis, pelvic inflammatory disease, acne, rosacea, and rickettsial infections
  • Inhibits the inflammatory response of Lyme disease
  • Used in prophylaxis of anthrax (caused by Bacillus anthracis)
  • Effective against Yersinia pestis
  • Inhibits collagen synthesis
  • Used in studies on wound healing and tissue remodeling
  • Eliminates Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs
  • Eliminates Ixodes scapularis ticks
Physical Form Powder
CAS 10592-13-9
Molecular Formula C22H25ClN2O8
MDL Number MFCD03427564
Synonym Biocamycin, Doxigalumicina, Doxycycline hyclate, Doxy-II, Midoxin, Novadox, Retens, Tetradox, Vibradox, Hydramycin, 2-Naphthacenecarboxamide, 4-(dimethylamino)- 1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride
Solubility Information Soluble in water (10mg/mL, clear, yellowish to yellowish-green solution) and DMSO (50mg/mL).
SMILES [Cl-].C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H]([NH+](C)C)C(=O)\C(=C(/N)O)C(=O)[C@@]3(O)C(=O)C2=C(O)C2=C(O)C=CC=C12
IUPAC Name [(1S,4aR,11R,11aR,12S,12aR)-3-carbamoyl-4,4a,6,7,12-pentahydroxy-11-methyl-2,5-dioxo-11,11a,12,12a-tetrahydro-1H-tetracen-1-yl]-dimethylazanium;chloride
Molecular Weight (g/mol) 480.90
PubChem CID 54706018
Formula Weight 480.9
Concentration Working Concentration: It is typically used at a concentration of 20ug/mL and is stable in media at 37°C for approximately 5 days.
Quantity 10 g
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Product Identifier
  • Doxycycline Hydrochloride
Signal Word
  • Warning
Hazard Category
  • Acute toxicity Category 4
  • Skin corrosion/irritation Category 2
  • Serious eye damage/eye irritation Category 2
  • Specific target organ toxicity Category 3
Hazard Statement
  • H302 + H312-Harmful if swallowed or in contact with skin.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321-Specific treatment (see on this label).
  • P405-Store locked up.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
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