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DR3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen DR3
Concentration 0.3 mg/mL
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16896855
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Proteintech
55397-1-AP-20UL
20 μL
1656.73 SEK
20µL
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Estimated Shipment: 03-04-2024
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16886855
View Documents Promotion Details
Proteintech
55397-1-AP-150UL
150 μL
4721.67 SEK
150µL
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Estimated Shipment: 03-04-2024
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Description

Description

This antibody can recognize all the isoform of TNFRSF25.

DR3/TNFRSF25 is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of DR3/TNFRSF25 in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predomitly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.
Specifications

Specifications

DR3
Western Blot
Unconjugated
Rabbit
Mouse, Human
Q93038
85030, 8718
Peptide
Primary
-20°C
TNFRSF25
0.3 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
APO 3, APO3, DDR3, Death receptor 3, DR3, LARD, Protein WSL, Protein WSL 1, TNFRSF12, TNFRSF25, TR3, TRAMP, WSL, WSL 1, WSL LR, WSL1
Tnfrsf25
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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