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DR3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
Antigen | DR3 |
---|---|
Concentration | 0.3 mg/mL |
Applications | Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16896855
|
Proteintech
55397-1-AP-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 03-04-2024 Log in to see stock. |
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16886855
|
Proteintech
55397-1-AP-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 03-04-2024 Log in to see stock. |
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Description
This antibody can recognize all the isoform of TNFRSF25.
DR3/TNFRSF25 is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of DR3/TNFRSF25 in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predomitly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.Specifications
DR3 | |
Western Blot | |
Unconjugated | |
Rabbit | |
Mouse, Human | |
Q93038 | |
85030, 8718 | |
Peptide | |
Primary | |
-20°C | |
TNFRSF25 |
0.3 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
APO 3, APO3, DDR3, Death receptor 3, DR3, LARD, Protein WSL, Protein WSL 1, TNFRSF12, TNFRSF25, TR3, TRAMP, WSL, WSL 1, WSL LR, WSL1 | |
Tnfrsf25 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |