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DYNLT1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11954-1-AP-20UL

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Product Code. 16879363

  • 1645.54 SEK / 20µL

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Description

Description

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. Is involved in intracellular targeting of D-type retrovirus gag polyproteins to the cytoplasmic assembly site. May also be a accessory component of axonemal dynein. Plays a role in neuronal morphogenesis; the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a receptor-independent activator of heterotrimeric G-protein signaling; the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis; inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2. Involved in the regulation of mitotic spindle orientation.
Specifications

Specifications

DYNLT1
Polyclonal
Unconjugated
DYNLT1
CW 1, DYNLT1, Protein CW 1, TCTEL1, tctex 1, TCTEX1
Rabbit
Antigen Affinity Chromatography
RUO
21648, 6993, 83462
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunoprecipitation, Immunocytochemistry
0.41 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P51807, P63172, Q9Z336
DYNLT1
DYNLT1 Fusion Protein Ag2557
20 μL
Primary
Mouse, Rat, Human
Antibody
IgG
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Product Title
DYNLT1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech > 20 μL; Unconjugated

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