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Dysadherin Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1355.00 SEK - 3665.00 SEK

Specifications

Antigen Dysadherin
Concentration 0.13 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16829713
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Proteintech
12166-1-AP-150UL
150 μL
3665.00 SEK
150µL
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Estimated Shipment: 07-02-2023
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16839713
View Documents Promotion Details
Proteintech
12166-1-AP-20UL
20 μL
1355.00 SEK
20µL
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Estimated Shipment: 07-02-2023
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Description

Description

This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na, K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, is a glycoprotein that functions in the up-regulation of chemokine production, and it is involved in the reduction of cell adhesion via its ability to down-regulate E-cadherin. It also promotes metastasis, and has been linked to a variety of cancers. Alternative splicing results in multiple transcript variants.
Specifications

Specifications

Dysadherin
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Mouse, Human
P97808, Q96DB9
18301, 53827
Dysadherin Fusion Protein Ag2808
Primary
-20°C
FXYD5
0.13 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
dysad, Dysadherin, FXYD5, HSPC113, IWU 1, IWU1, KCT1, OIT2, PRO6241, RIC, UNQ2561/PRO6241
Fxyd5
IgG
Antigen Affinity Chromatography
Antibody
SDS
Product Certifications