missing translation for 'onlineSavingsMsg'
Learn More

E-cadherin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen E-cadherin
Concentration 0.34 mg/mL
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Polyclonal
Conjugate Unconjugated
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16850455
View Documents Promotion Details
Proteintech
20874-1-AP-20UL
20 μL
1656.73 SEK
20µL
View alternative products
Save Up to 
»
Estimated Shipment: 03-04-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
16840455
View Documents Promotion Details
Proteintech
20874-1-AP-150UL
150 μL
4721.67 SEK
150µL
View alternative products
Save Up to 
»
Estimated Shipment: 03-04-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
Description

Description

This polyclonal antibody recognizes 120 kDa intact E-cadherin and its 80 kDa trypsin-cleaved fragment.

E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintece of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.
Specifications

Specifications

E-cadherin
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Unconjugated
Rabbit
Rat, Human, Mouse
P09803, P12830, Q9R0T4
12550, 83502, 999
E-cadherin Fusion Protein Ag14973
Primary
-20°C
CDH1
0.34 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Arc 1, Cadherin 1, CD324, CDH1, CDHE, E cadherin, ECAD, E-cadherin, LCAM, UVO, Uvomorulin
Cdh1
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

Product Certifications