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EIF3C Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1355.00 SEK - 3665.00 SEK

Specifications

Antigen EIF3C
Concentration 0.4 mg/mL
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16840614
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Proteintech
12733-1-AP-150UL
150 μL
3665.00 SEK
150µL
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Estimated Shipment: 07-12-2022
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16850614
View Documents Promotion Details
Proteintech
12733-1-AP-20UL
20 μL
1355.00 SEK
20µL
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Estimated Shipment: 07-12-2022
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Description

Description

Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (5′ to 3′) activity. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. RUVBL2 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex. May also inhibit the transcriptional activity of ATF2.
Specifications

Specifications

EIF3C
Immunoprecipitation, Western Blot
Unconjugated
Rabbit
Rat, Mouse, Human
B5DFC8, Q8R1B4, Q99613
293484, 56347, 8663
EIF3C Fusion Protein Ag3438
Primary
-20°C
EIF3C
0.4 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
eIF3 p110, EIF3C, EIF3CL, EIF3S8
EIF3C
IgG
Antigen Affinity Chromatography
Antibody
SDS
Product Certifications