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EIF3D Mouse anti-Human, Mouse, Rat, Clone: 2C5A3, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66024-1-IG-150UL
Additional Details : Weight : 0.00010kg
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DescriptioneIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3). eIF3 is a multiprotein complex composed of at least 13 different subunits. eIF3D binds to the 40S ribosomal subunit and thus helps in maintaining the 40S and 60S ribosomal subunits in a dissociated state. An important role of eIF3D is the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and promotes mRNA binding. eIF3D is the major RNA binding subunit of the eIF3 complex. It associates with the subunit p170 of eIF-3. Ubiquitous expression of eIF3D is seen in most of the tissues and it is phosphorylated upon DNA damage, likely by ATM or ATR.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|O15371, O70194, Q6AYK8|
|EIF3D Fusion Protein Ag18092|
|Rat, Mouse, Human|
|Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry|
|eIF 3 zeta, eIF3 p66, eIF3 zeta, EIF3D, EIF3S7|
|362952, 55944, 8664|