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EYA2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11314-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888303

  • 1656.73 SEK / 20µL
Estimated Shipment: 03-04-2024
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Description

Description

Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates ′Tyr- 142′ of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. ′Tyr-142′ phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1.
Specifications

Specifications

EYA2
Polyclonal
Unconjugated
EYA2
EAB1, EYA2, Eyes absent homolog 2
Rabbit
Antigen Affinity Chromatography
RUO
14049, 156826, 2139
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence, Western Blot
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O00167, O08575
EYA2
EYA2 Fusion Protein Ag1860
20 μL
Primary
Mouse, Human, Rat
Antibody
IgG
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