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F4/80 Monoclonal Antibody (BM8), Functional Grade, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 16-4801-050
Beskrivning
The BM8 MAb reacts with mouse F4/80 antigen, an approximately 125 kDa transmembrane protein. The F4/80 antigen is expressed by a majority of mature macrophages and is the best marker for this population of cells. However, other cell types such as Langerhans cells and liver Kupffer cells have been reported to express this antigen. Expression of F4/80 commences during early myeloid development and is upregulated on all BM cells stimulated in vitro with M-CSF. It has been shown that some cytokines downregulate the expression of F4/80 resulting in lack of F4/80 antigen on a subpopulation of macrophages, especially in the lymphoid microenvironment in vivo.
F4/80 Monoclonal antibody specifically detects F4/80 in Mouse samples. It is validated for Control, Flow Cytometry, Functional Assay
Specifikationer
| F4/80 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative; pH 7.2 | |
| Q61549 | |
| Rat | |
| 50 mg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a κ |
| Flow Cytometry, Functional Assay | |
| BM8 | |
| Functional Grade | |
| ADGRE1 | |
| ADGRE1; adhesion G protein-coupled receptor E1; Cell surface glycoprotein F4/80; DD7A5-7; egf-like module containing, mucin-like, hormone receptor-like 1; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-TM7; EMR1; EMR1 hormone receptor; F4/80; Gpf480; Ly71; lymphocyte antigen 71; TM7LN3 | |
| Affinity chromatography | |
| RUO | |
| 13733 | |
| 4° C | |
| Liquid |
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