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Factor X Mouse anti-Human, Clone: 3D3F11, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66753-1-IG-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888915

  • 1656.73 SEK / 20µL
Estimated Shipment: 03-04-2024
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Description

Description

F10 undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
Specifications

Specifications

Factor X
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P00742
F10
Factor X Fusion Protein Ag11664
20 μL
Primary
Human
Antibody
IgG1
Western Blot
3D3F11
Unconjugated
F10
coagulation factor X, F10, Factor X, FX, FXA, Stuart factor, Stuart Prower factor
Mouse
Protein G
RUO
2159
-20°C
Liquid
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