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Fc epsilon RI alpha Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10980-1-AP-20UL

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Product Code. 16887723

  • 1645.54 SEK / 20µL

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Description

Description

FceR1 (Fc epsilonR1 alpha) is a subunit of the high affinity receptor of IgE. Fc epsilonR1 alpha is a tetrameric complex consisting of one alpha, one beta and two additional subunits. The latter two are required for signal transduction activity. The Fc epsilonR1 complex plays an important role in triggering allergic responses, and the immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine, which are responsible for allergy symptoms, are released. The IgE receptor couples allergen and mast cells to initiate the inflammatory responses that are characteristic of disorders such as hay fever and asthma. The release of histamine and proteases leads to the synthesis of prostaglandins and leukotrienes-potent effectors of the hypersensitivity response.
Specifications

Specifications

Fc epsilon RI alpha
Polyclonal
Unconjugated
FCER1A
Fc epsilon RI alpha, FCE1A, FCER1A, FcERI, FceRIa, IgE Fc receptor subunit alpha
Rabbit
Antigen Affinity Chromatography
RUO
14125, 2205
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.13 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P12319, P20489
FCER1A
Fc epsilon RI alpha Fusion Protein Ag1398
20 μL
Primary
Human, Mouse
Antibody
IgG
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Fc epsilon RI alpha Rabbit anti-Human, Mouse, Polyclonal, Proteintech > 20 μL; Unconjugated

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