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Invitrogen™ Human FLT1 (VEGFR1), GST Tag Recombinant Protein

Recombinant Protein

21540.00 SEK - 139200.00 SEK

Specifications

Accession Number P17948
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 2321
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15488483
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Invitrogen™
PR6731B
100 ÎĽg
21540.00 SEK
100µg
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10087082
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Invitrogen™
PR6731A
1 mg
139200.00 SEK
1mg
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Description

Description

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 ÎĽg, 10 ÎĽg and 20 ÎĽg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 ÎĽL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Cytoplasmic

FLT1 (VEGFR1) is a receptor tyrosine kinase which plays a critical role in angiogenesis. Active angiogenesis has been found to play important role in many pathological and physiological processes, such as tumor progression, diabetic retinopathy, rheumatoid arthritis and wound healing. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. Promotes PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro). Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR.
Specifications
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Invitrogen™ Human FLT1 (VEGFR1), GST Tag Recombinant Protein

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