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Invitrogen™ Human FLT1 (VEGFR1), GST Tag Recombinant Protein
Recombinant Protein
21540.00 SEK - 139200.00 SEK
Specifications
Accession Number | P17948 |
---|---|
Concentration | See Label |
For Use With (Application) | Kinase Assay |
Formulation | 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5 |
Gene ID (Entrez) | 2321 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15488483
|
Invitrogen™
PR6731B |
100 ÎĽg |
21540.00 SEK
100µg |
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10087082
|
Invitrogen™
PR6731A |
1 mg |
139200.00 SEK
1mg |
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Description
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 ÎĽg, 10 ÎĽg and 20 ÎĽg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 ÎĽL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Cytoplasmic
FLT1 (VEGFR1) is a receptor tyrosine kinase which plays a critical role in angiogenesis. Active angiogenesis has been found to play important role in many pathological and physiological processes, such as tumor progression, diabetic retinopathy, rheumatoid arthritis and wound healing. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. Promotes PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro). Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR.Specifications
P17948 | |
Kinase Assay | |
2321 | |
Human FLT1 (VEGFR1), GST Tag | |
AI323757; embryonic receptor kinase 2; Emrk2; FLT; FLT1; FLT-1; fms related tyrosine kinase 1; FMS-like tyrosine kinase 1; FMS-related tyrosine kinase 1; Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); FRT; i21; sFlt1; soluble VEGFR 1; sVEGFR 1; Tyrosine-protein kinase FRT; tyrosine-protein kinase receptor FLT; Vascular endothelial growth factor receptor 1; vascular endothelial growth factor receptor-1; vascular permeability factor receptor; VEGF R1; VEGFR1; VEGFR-1 | |
VEGF Receptors | |
Unconjugated | |
Recombinant | |
-80°C, Avoid Freeze/Thaw Cycles | |
Liquid |
See Label | |
50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5 | |
92.6 kDa | |
RUO - research use only | |
VEGF Receptor 1 | |
781-1338 | |
Human | |
GST-tag | |
Insect cells |
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