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FPGT Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 24937-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose.Specifications
FPGT | |
Polyclonal | |
Unconjugated | |
FPGT | |
FPGT, GDP L fucose diphosphorylase, GDP L fucose pyrophosphorylase, GFPP | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
75540, 8790 | |
-20°C | |
Liquid |
Western Blot, Immunohistochemistry (Paraffin) | |
0.47 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
G5E8F4, O14772 | |
FPGT | |
FPGT Fusion Protein Ag20655 | |
20 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |