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Frizzled 8 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 55093-1-AP-150UL
Additional Details : Weight : 0.00010kg
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DescriptionMembers of the Frizzled family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Frizzled 8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. Its expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
|Frizzled 8, FZ 8, FZD8, hFZ8|
|Antigen Affinity Chromatography|
|Western Blot, Immunohistochemistry (Paraffin)|
|0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3|