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GABRA1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
Antigen | GABRA1 |
---|---|
Concentration | 0.23 mg/mL |
Applications | Flow Cytometry, Immunoprecipitation, Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16890114
|
Proteintech
12410-1-AP-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 19-04-2024 Log in to see stock. |
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16880114
|
Proteintech
12410-1-AP-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 19-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Gamma -aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA Receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date aix alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for alpha- and beta-subunits results in the expression of functional GABAA-R sensitive to GABA. However, coexpression of a gamma-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different alpha-subunits of the receptor. Lastly, phosphorylation of beta-subunits of the receptor has been shown to modulate GABAA-R function.Specifications
GABRA1 | |
Flow Cytometry, Immunoprecipitation, Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
P14867, P62812, P62813 | |
14394, 2554, 29705 | |
GABRA1 Fusion Protein Ag3117 | |
Primary | |
-20°C | |
GABRA1 |
0.23 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
ECA4, EJM, GABA A receptor alpha 1, GABAA receptor alpha 1, GABRA1 | |
Gabra1 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |