missing translation for 'onlineSavingsMsg'
Learn More

GAD1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10408-1-AP-150UL

Additional Details : Weight : 0.00010kg

 View more versions of this product

Product Code. 16876773

  • 4721.67 SEK / 150µL
Estimated Shipment: 03-04-2024
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in the brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 will transiently activate to assist in GABA production. The loss of GAD-65 is detrimental and can impair GABA neurotransmission, however the loss of GAD-67 is lethal. Due to alternative splicing, two isoforms exist for GAD-67: the predomit GAD-67 form and the minor GAD-25 form.
Specifications

Specifications

GAD1
Polyclonal
Unconjugated
GAD1
GAD, GAD 67, GAD1, GAD67, Glutamate decarboxylase 1, SCP
Rabbit
Antigen Affinity Chromatography
RUO
14415, 24379, 2571
-20°C
Liquid
Immunoprecipitation, Western Blot
0.29 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P18088, P48318, Q99259
Gad1
GAD1 Fusion Protein Ag0666
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers