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GAD1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 10408-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in the brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 will transiently activate to assist in GABA production. The loss of GAD-65 is detrimental and can impair GABA neurotransmission, however the loss of GAD-67 is lethal. Due to alternative splicing, two isoforms exist for GAD-67: the predomit GAD-67 form and the minor GAD-25 form.Specifications
GAD1 | |
Polyclonal | |
Unconjugated | |
GAD1 | |
GAD, GAD 67, GAD1, GAD67, Glutamate decarboxylase 1, SCP | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
14415, 24379, 2571 | |
-20°C | |
Liquid |
Immunoprecipitation, Western Blot | |
0.29 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P18088, P48318, Q99259 | |
Gad1 | |
GAD1 Fusion Protein Ag0666 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |