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GAD1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10408-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16876773

  • 3313.85 SEK / 150µL
Estimated Shipment: 07-12-2021

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Description

Description

GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in the brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 will transiently activate to assist in GABA production. The loss of GAD-65 is detrimental and can impair GABA neurotransmission, however the loss of GAD-67 is lethal. Due to alternative splicing, two isoforms exist for GAD-67: the predomit GAD-67 form and the minor GAD-25 form.
Specifications

Specifications

GAD1
0.29 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P18088, P48318, Q99259
GAD, GAD 67, GAD1, GAD67, Glutamate decarboxylase 1, SCP
Rabbit
IgG
150 μL
-20°C
Primary
14415, 24379, 2571
Immunoprecipitation, Western Blot
Unconjugated
GAD1
Liquid
Gad1
GAD1 Fusion Protein Ag0666
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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