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Gibco™ Human Oncostatin M Recombinant Protein Product Code.: 10660154

Gibco™ Human Oncostatin M Recombinant Protein

Product Code. 10660154
10 μg, Each
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Quantity:
10 μg
Unit Size:
Each
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For Research Use Only. All usage must comply with product instructions.

Product Code. 10660154

Brand: Gibco™ PHC5015

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This item is not returnable. View return policy

For Research Use Only. All usage must comply with product instructions.

Recombinant Protein

Carrier-Free Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute human oncostatin M in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2°C to 8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein, such as 0.1% BSA and store in working aliquots at -20°C to -80°C. Storage: The lyophilized protein is stable at room temperature for 1 month, but should be kept at -20°C for long term storage, preferably desiccated. Working aliquots stored with a carrier protein are stable for at least 3 months at -80°C to -20°C. Avoid repeated freeze/thaw cycles.

Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P13725
For Use With (Application) Control, ELISA, Functional Assay, Immunohistochemistry, Western Blot
Formulation protein with no preservative
Gene ID (Entrez) 5008
Molecular Weight (g/mol) 26 kDa
Name Human Oncostatin M
Purification Method Sequential Chromatography
Quantity 10 μg
Endotoxin Concentration <0.1 ng/ μg
Gene Alias MGC20461; OncoM; oncostatin M; oncostatin-M; OSM
Common Name Oncostatin M
Biological Activity ED50 ≤ 2 ng/mL; determined by the dose-dependent proliferation of TF-1 cells.
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Sequence Human Oncostatin M recombinant protein contains 227 amino acids
Content And Storage -20°C
Classification Carrier-Free
Endotoxin Level <0.1 ng/μg
Shipping Condition Approved for shipment on Wet or Dry Ice
Expression System E. coli
Protein Family Cytokines & Receptors
Protein Form Recombinant, Ligand
Form Lyophilized
Protein Subtype Other Proteins
Research Category Immunology, Signal Transduction, Stem Cell Research, Inflammation, Differentiation, Oncology
Product Line Gibco™
Purity or Quality Grade ≥98% by SDS-PAGE and HPLC
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3 results found
Lot Number Certificate Type Date Product Code
Lot Number74773257A Certificate TypeCertificate of Analysis Date15/12/2017 Product CodePHC5015
Lot Number74944653A Certificate TypeCertificate of Analysis Date15/12/2017 Product CodePHC5015
Lot Number74765963A Certificate TypeCertificate of Analysis Date05/12/2017 Product CodePHC5015
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