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GJB3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 12880-1-AP-150UL
Additional Details : Weight : 0.00010kg
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DescriptionGap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variabilis (EKV) is an autosomal domit genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.
|Connexin 31, CX31, DFNA2, DFNA2B, EKV, Gap junction beta 3 protein, GJB3|
|Antigen Affinity Chromatography|
|14620, 2707, 29585|
|Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry|
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|O75712, P25305, P28231|
|GJB3 Fusion Protein Ag3839|
|Rat, Mouse, Human|