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GNAI3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 11641-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, beta and gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of Galpha subunits have been identified; these include Gs, Gi, Gq and Galpha 12/13. The Gi class comprises all the known alpha subunits that are susceptible to pertussis toxin modifications, including Galpha i-1, Galpha i-2, Galpha i-3, Galpha o, Galpha t1, Galpha t2, Galpha z and Galpha gust. Of these, the three Galpha i subtypes function to open atrial potassium channels.Specifications
GNAI3 | |
Polyclonal | |
Unconjugated | |
GNAI3 | |
87U6, G(i) alpha 3, GNAI3 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
14679, 25643, 2773 | |
-20°C | |
Liquid |
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry, Flow Cytometry | |
0.13 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P08753, P08754, Q9DC51 | |
GNAI3 | |
GNAI3 Fusion Protein Ag2229 | |
150 μL | |
Primary | |
Rat, Mouse, Human | |
Antibody | |
IgG |