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  6. GRAMD4 Rabbit anti-Human, Polyclonal, Proteintech

GRAMD4 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1645.54 SEK - 4652.90 SEK

Specifications

Antigen GRAMD4
Concentration 0.59 mg/mL
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
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16882775
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Proteintech
24299-1-AP-20UL 		20 ÎĽL
1645.54 SEK
20µL
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16872775
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Proteintech
24299-1-AP-150UL 		150 ÎĽL
4652.90 SEK
150µL
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Description

Description

GRAMD4 also termed as Death inducing protein is a 578 amino-acid protein, which contains 1 GRAM domain. GRAMD4 as a multi-pass membrane protein localizes in the Mitochondrion membrane. Overexpression of GRAMD4 results in a strong apoptotic response involving caspase-3 activation and cleavage of poly (ADP-ribose)-polymerase. GRAMD4 is expressed in lung and in primary lung squamous cell carcinoma (LSCC) and shows up-regulation in mitochondria by E2F-1 after addition of 4-hydroxytamoxifen. This evidence suggests that GRAMD4 may be a potential target for cancer therapies.
Specifications

Specifications

GRAMD4
Western Blot
Unconjugated
Rabbit
Human
Q6IC98
23151
GRAMD4 Fusion Protein Ag19140
Primary
-20°C
GRAMD4
0.59 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
dA59H18.1, Death inducing protein, DIP, GRAM domain containing 4, GRAMD4, KIAA0767
GRAMD4
IgG
Antigen Affinity Chromatography
Antibody
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