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GRIN2B Mouse anti-Human, Mouse, Rat, Clone: 1C5E12, Proteintech

Mouse Monoclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen GRIN2B
Clone 1C5E12
Concentration 0.66 mg/mL
Applications Western Blot
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16888555
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Proteintech
66565-1-IG-20UL
20 μL
1656.73 SEK
20µL
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Estimated Shipment: 03-04-2024
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16878555
View Documents Promotion Details
Proteintech
66565-1-IG-150UL
150 μL
4721.67 SEK
150µL
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Estimated Shipment: 03-04-2024
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Description

Description

NMDAR2B is a member of the N-methyl-D-aspartate (NMDA) class of ionotropic glutamate receptors. NMDA receptors (NMDAR) have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDAR play a role in neuronal development and has been implicated in several disorders of the central nervous system including Alzheimer′s Disease, epilepsy and ischemic neuronal cell death. Overexpression of the NR2B subunit of the receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression. Tyr1472 on NR2B is phosphorylated and this may lead to the increased expression of the NMDAR at the synapse that plays a role in synaptic plasticity. NMDR2B is a heterotrimer comprised of seven enetically encoded and differentially expressed subunits that include NR1, NR2 and NR3. Diseases associated with the dysfunction of NMDAR2B include epileptic encephalopathy, autosomal domit 6-related mental retardation.
Specifications

Specifications

GRIN2B
0.66 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
GluN2B, GRIN2B, hNR3, NMDAR2B, NR2B, NR3
GRIN2B
IgG1
Protein G
Antibody
1C5E12
Western Blot
Unconjugated
Mouse
Human, Mouse, Rat
Q00960, Q01097, Q13224
14812, 24410, 2904
GRIN2B Fusion Protein Ag16718
Primary
-20°C
GRIN2B
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SDS
Documents

Documents

Product Certifications