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GSK2578215A

Potent, selective LRRK2 inhibitor; brain penetrant

Brand:  Tocris 4629/5

Additional Details : Weight : 0.00970kg

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Product Code. 18065002

  • 1994.21 SEK / 5mg
Estimated Shipment: 17-07-2024
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Description

Description

GSK2578215A is a potent LRRK2 inhibitor (IC50 values are 8.9 and 10.1 nM for LRRK2[G2019S] mutant and wild-type LRRK2 respectively). Displays selectivity for LRRK2 over a panel of 460 other kinases. Blocks Ser910 and Ser935 phosphorylation in vitro and in peripheral tissues in vivo. Brain penetrant.
Specifications

Specifications

5-(2-Fluoro-4-pyridinyl)-2-(phenylmethoxy)-N-3-pyridinylbenzamide
>99%
C24H18FN3O2
1285515-21-0
5 mg
Observed MW: 399.42
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