missing translation for 'onlineSavingsMsg'
Learn More

GUK1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen GUK1
Concentration 0.25 mg/mL
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16897343
View Documents Promotion Details
Proteintech
10755-1-AP-20UL
20 μL
1656.73 SEK
20µL
View alternative products
Save Up to 
»
Estimated Shipment: 02-04-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
16887343
View Documents Promotion Details
Proteintech
10755-1-AP-150UL
150 μL
4721.67 SEK
150µL
View alternative products
Save Up to 
»
Estimated Shipment: 02-04-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
Description

Description

Guanylate kinase (GK) catalyzes the ATP-dependent phosphorylation of GMP into GDP. It is essential for recycling GMP and indirectly, cGMP. In prokaryotes (such as Escherichia coli), lower eukaryotes (such as yeast) and in vertebrates, GK is a highly conserved monomeric protein of about 200 amino acids. GK has been shown to be structurally similar to protein A57R (or SalG2R) from various strains of Vaccinia virus. Proteins containing one or more copies of the DHR domain, an SH3 domain as well as a C-terminal GK-like domain, are collectively termed MAGUKs (membrane-associated guanylate kinase homologs) and include Drosophila lethal(1)discs large-1 tumor suppressor protein (gene dlg1); mammalian tight junction protein Zo-1; a family of mammalian synaptic proteins that seem to interact with the cytoplasmic tail of NMDA receptor subunits (SAP90/PSD-95, CHAPSYN-110/PSD-93, SAP97/DLG1 and SAP102); vertebrate 55 kD erythrocyte membrane protein (p55); C. elegans protein lin-2; rat protein CASK; and human proteins DLG2 and DLG3. There is an ATP-binding site (P-loop) in the N-terminal section of GK, which is not conserved in the GK-like domain of the above proteins. However these proteins retain the residues known, in GK, to be involved in the binding of MP.
Specifications

Specifications

GUK1
Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Human, Mouse, Rat
Q16774, Q64520
14923, 2987, 303179
GUK1 Fusion Protein Ag1205
Primary
-20°C
GUK1
0.25 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
GMK, GMP kinase, Guanylate kinase, guanylate kinase 1, GUK1
Guk1
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

Product Certifications