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HOXB4 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 22256-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
HOX homeobox genes play a role both in the early stem cell function as well as in later stages of hematopoietic differentiation. HOXB4, specifically, is a homeotic selector gene implicated in self-renewal of definitive HSCs. Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induced a switch to the definitive HSC phenotype. Activation of WNT signaling in HSCs induced increased expression of HOXB4. Perturbations of HOX gene expression can cause leukemia.Specifications
| HOXB4 | |
| Polyclonal | |
| Unconjugated | |
| HOXB4 | |
| homeobox B4, Homeobox protein Hox 2.6, Homeobox protein Hox 2F, Homeobox protein Hox B4, HOX 2.6, HOX2, HOX2F, HOXB4 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 3214 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 0.28 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P17483 | |
| HOXB4 | |
| HOXB4 Fusion Protein Ag17761 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |