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HSP70 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10995-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16887753

  • 1236.20 SEK / 20µL
Estimated Shipment: 07-12-2021

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Description

Description

This antibody well recognized the endogenous HSP70 protein in multiple cell lines.

HSP70 is a Heat shock protein (HSP) which are expressed in response to various biological stresses, including high temperatures. There are several major families of HSPs that include HSP70, there are HSP90 and HSP100. The HSP70 family is a set of highly conserved proteins that are induced by a variety of biological stresses, including heat stress, in every organism in which the proteins have been examined. The human HSP70 family members include: HSP70, a protein which is strongly inducible in all organisms but which is also constitutively expressed in primate cells; HSP72, a 72 kDa protein that is induced exclusively under stress conditions; HSC70, or cognate protein, is a 72 kDa, constitutively expressed, protein which is involved in the uncoating of clathrin coated vesicles; GRP78, or BiP, is a glucose regulated 78 kDa protein localized in the endoplasmic reticulum; and p75, or HSP75, a 75 kDa protein that is found within the mitochondria. Further, HSP70 is encoded by an intronless gene and, in conjunction with other heat shock proteins, HSP70 stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and organelles. HSP70 is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The HSP70 gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
Specifications

Specifications

HSP70
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P0DMV8, P0DMW0, Q61696
Heat shock 70 kDa protein 1/2, heat shock 70kDa protein 1A, HSP70, HSP70 1, HSP70 1/HSP70 2, HSP70 1A, HSP70.1/HSP70.2, HSP70I, HSP72, HSPA1, HSPA1A, HSPA1B
Rabbit
IgG
20 μL
-20°C
Primary
193740, 24472, 3303
Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence, Immunoprecipitation
Unconjugated
HSPA1A
Liquid
HSPA1A
HSP70 Fusion Protein Ag1446
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Human, Rat
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