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Invitrogen™ Human ESRP1 (aa 23-102) Control Fragment Recombinant Protein
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Quantity:
100 μL
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100µL
Description
Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84744 (PA5-84744. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.

Spécification
Spécification
Accession Number | Q6NXG1 |
Concentration | ≥5.0 mg/mL |
For Use With (Application) | Blocking Assay, Control |
Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
Gene ID (Entrez) | 54845 |
Name | Human ESRP1 (aa 23-102) Control Fragment |
Quantity | 100 μL |
Regulatory Status | RUO |
Gene Alias | 2210008M09Rik; A630065D16; BC031468; epithelial splicing regulatory protein 1; Esrp1; Rbm35a; RGD1560481; RMB35A; RNA binding motif protein 35 A; RNA-binding motif protein 35 A; RNA-binding protein 35 A |
Common Name | ESRP1 |
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