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STEMCELL Technologies Human Recombinant bFGF
Basic fibroblast growth factor
Brand: STEMCELL Technologies 78003.2
Additional Details : Weight : 0.00001kg
Description
- Basic fibroblast growth factor (bFGF) is a prototypic member of the fibroblast growth factor family
- Cytokines in the FGF family possess broad mitogenic and cell survival activities (Folkman & Klagsbrun; Kimelman & Kirschner) and are involved in a variety of biological processes including cell proliferation, differentiation, survival, and apoptosis (Folkman & Klagsbrun; Klagsbrun; Rifkin & Moscatelli)
- bFGF has the β-trefoil structure (Ponting & Russell), binds to the four FGF receptor (FGFR) family members, and activates JAK/STAT, PI3K, ERK1/2, and other receptor tyrosine kinase (RTK) signaling pathways
- It supports the maintenance of undifferentiated human embryonic stem cells (Xu et al.; Kang et al.), stimulates human embryonic stem cells to form neural rosettes (Zhang et al.), and improves proliferation of human mesenchymal stem cells and enhances chondrogenic differentiation (Solchaga et al.)
Specifications
| Basic fibroblast growth factor, FGF-β, FGF2, Fibroblast growth factor-basic, HBGF-2 | |
| >95% | |
| 1000 μg | |
| Brain Tumor Stem Cells; Endoderm, PSC-Derived; Hematopoietic Stem and Progenitor Cells; Mesenchymal Stem and Progenitor Cells; Mesoderm, PSC-Derived; Neural Cells, PSC-Derived; Neural Stem and Progenitor Cells; Neurons; Pluripotent Stem Cells; Prostate Cells |