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STEMCELL Technologies Human Recombinant CNTF, ACF

Ciliary neurotrophic factor, animal component-free

Brand:  STEMCELL Technologies 78170.2

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Product Code. 17199741

  • 43426.80 SEK / 1000µg

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Description

Description

  • Ciliary neurotrophic factor (CNTF) is a neurotrophic factor that belongs to the four-helix bundle cytokine family and is structurally related to interleukin 6 (IL-6), interleukin 11 (IL-11), leukemia inhibitory factor (LIF), and oncostatin M (OSM)
  • CNTF binds to its receptor CNFTRα and induces formation of a heterodimer of the signal transducing IL-6 receptor gp130 and LIF receptor (LIFR)-β, which triggers JAK/STAT, ERK, and PI3K signaling cascades
  • CNTF plays an important role in neurogenesis and the differentiation of neural stem cells and has been suggested to possess a therapeutic role in treating neurological disorders
  • Additionally, CNTF is commonly used to differentiate human pluripotent stem cell (hPSC)-derived neural progenitor cells into astrocytes
  • This product is animal component-free
Specifications

Specifications

Ciliary neurotrophic factor, HCNTF
1000 μg
Neural Cells, PSC-Derived; Neural Stem and Progenitor Cells; Neurons
≥95%
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