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STEMCELL Technologies Human Recombinant CNTF, ACF
Ciliary neurotrophic factor, animal component-free
Brand: STEMCELL Technologies 78170.2
This item is not returnable.
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Description
- Ciliary neurotrophic factor (CNTF) is a neurotrophic factor that belongs to the four-helix bundle cytokine family and is structurally related to interleukin 6 (IL-6), interleukin 11 (IL-11), leukemia inhibitory factor (LIF), and oncostatin M (OSM)
- CNTF binds to its receptor CNFTRα and induces formation of a heterodimer of the signal transducing IL-6 receptor gp130 and LIF receptor (LIFR)-β, which triggers JAK/STAT, ERK, and PI3K signaling cascades
- CNTF plays an important role in neurogenesis and the differentiation of neural stem cells and has been suggested to possess a therapeutic role in treating neurological disorders
- Additionally, CNTF is commonly used to differentiate human pluripotent stem cell (hPSC)-derived neural progenitor cells into astrocytes
- This product is animal component-free
Specifications
| Ciliary neurotrophic factor, HCNTF | |
| 1000 μg | |
| Neural Cells, PSC-Derived; Neural Stem and Progenitor Cells; Neurons | |
| ≥95% |
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STEMCELL Technologies Human Recombinant CNTF, ACF
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